Qing-Hong Shi


Room 302, Experimental Centre of Fundamental Chemical Engineering
School of Chemical Engineering and Technology, Tianjin University
No.92, Weijin Road
Nankai District, Tianjin
P.R. China, 300354

Tel: 86-22-2740 2048
Email: qhshi@tju.edu.cn

 
Education
Ph. D., Chemical Engineering, Tianjin University, 1998
M.S., Chemical Engineering, Tianjin University, 1994　
B.S., Chemical Engineering, Tianjin University, 1991
 
Research Interests

High-efficient chromatographic techniques of biological molecules
Thermodynamics of protein interaction

 
Experiences

Associate Professor, Department of Biochemical Engineering, Tianjin University (09/2002-present)
Co-investigator, Department of Research and Development, Beijing Kaizheng Biotechnology Development Ltd. Co. (07/1998-08/2002)

 
Projects

The production and clinical trial of artificial blood substitutes, supported by National High Technology Research and Development Program (NHTRDP, grant No. Z-18-02), 1998-2002;
The Study of artificial blood substitutes – the production of albumin-based serum replacement agent, supported by NHTRDP (grant No. Z-18-03), 2000-2002;
The study of adsorption and diffusion mechanism of multi- component proteins with the aid of confocal laser scanning microscopy, supported by National Natural Science Foundation of China(NSFC, grant No. 20306024), Principle investigator, 2004-2006;
Real-time measurement of protein diffusion in gels with the aid of confocal laser scanning microscopy, supported by Tianjin Applied and Fundamental Research Program (grant No. 0436048-11), principle investigator, 2004-2006;
Polymeric vector engineering for gene delivery: From the analysis of viral proteins to the synthesis of polymeric vectors, supported by NSFC (grant No. 20676099), principle investigator, 2007-2009

 
Publications
  1. Shi Q-H, Sun Y, Liu L  and Bai S. Distribution behavior of amino acid by extraction with di(2-ethylhexyl) phosphoric acid. Separation Science and Technology. 1997; 32 (12): 2051-2067.
  2. Shi Q-H, Tian Y, Dong X-Y, Bai S and Sun Y. Chitosan coated silica as immobilized metal affinity support for protein adsorption. Biochem Eng J. 2003; 16 (3): 317-322.
  3. Shi Q-H, Zhou X, Sun Y. A novel superporous agarose medium for high-speed protein chromatography. Biotechnol Bioeng. 2005; 92(5): 643- 651.
  4. Shi Q-H, Zhou Y, Sun Y. Influence of pH and ionic strength on the steric mass-action model parameters around the isoelectric point of protein. Biotechnol Prog. 2005;21(2):516-523.
  5. Shi Q-H, Yang J, Su L, Sun Y. Synthesis and characterization of novel amino acid-based dendritic displacer. J Chem Ind Eng (Chinese). 2007; 58(5): 1271-1276
  6. Shi Q-H, Peng G-Y, Sun S, Sun Y. Process Intensification and Characterization of Agarose Gel Activation with Epichlorohydrin. Chin J Proc Eng (Chinese). 2007; 7(4): 743-746
  7. Sun Y, Liu F-F, Shi Q-H. Approaches to High- Performance Preparative Chromatography of Proteins (Invited paper). Adv Biochem Eng Biotechnol. 2009; 113: 217-254
  8. Zhang W, Shi Q-H. Development of Starburst PAMAM Dendrimers as Gene Vector. Chem Ind Eng (Chinese). 2009; 26(2): 165-168.
  9. Shi Q-H, Shen F-F, Sun S. Studies of Lysozyme Binding to Histamine as a Ligand for Hydrophobic Charge Induction Chromatography. Biotechnol Prog. 2009; DOI: 10.1002/btpr.295
  10. Shi Q-H, Cheng Z, Sun Y. Studies of Lysozyme Binding to Histamine as a Ligand for Hydrophobic Charge Induction Chromatography. J chromatogr A. 2009; 1216(33): 6081-6087